Hinrich Gronemeyer Selected Research

4- (2- (5,6,7,8- tetrahydro- 3,5,5,8,8- pentamethyl- 2- naphthalenyl)- 1- propenyl)benzoic acid

9/2007

Silicon analogues of the retinoid agonists TTNPB and 3-methyl-TTNPB, disila-TTNPB and disila-3-methyl-TTNPB: chemistry and biology.

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Hinrich Gronemeyer Research Topics

Disease

40	Neoplasms (Cancer) 01/2022 - 05/2002
12	Acute Promyelocytic Leukemia 08/2015 - 05/2002
9	Leukemia 12/2012 - 05/2002
5	Metabolic Diseases (Metabolic Disease) 01/2012 - 10/2007
4	Breast Neoplasms (Breast Cancer) 04/2015 - 08/2004
3	Carcinogenesis 01/2016 - 04/2011
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2005 - 02/2004
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2012 - 01/2007
2	Obesity 01/2012 - 11/2004
2	Genetic Translocation (Chromosomal Translocation) 02/2004 - 01/2004
1	Carcinoma (Carcinomatosis) 01/2018
1	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 08/2015
1	Lymphoma (Lymphomas) 01/2015
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 02/2013
1	Type 2 Diabetes Mellitus (MODY) 01/2012
1	Hepatomegaly 01/2012
1	Insulin Resistance 01/2012
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2011
1	Skin Diseases (Skin Disease) 01/2011
1	Colonic Neoplasms (Colon Cancer) 02/2010
1	Neuroblastoma 04/2009
1	Kaposi Sarcoma (Kaposi's Sarcoma) 01/2008
1	Infections 01/2008
1	Melanoma (Melanoma, Malignant) 11/2007
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2007

Drug/Important Bio-Agent (IBA)

15	RetinoidsIBA 01/2018 - 05/2002
14	LigandsIBA 01/2017 - 05/2002
9	Tretinoin (Retinoic Acid)FDA LinkGeneric 08/2015 - 05/2002
7	Proteins (Proteins, Gene)FDA Link 01/2017 - 02/2004
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017 - 10/2005
5	ChromatinIBA 01/2016 - 08/2004
5	Histone Deacetylases (Histone Deacetylase)IBA 02/2013 - 01/2005
4	Histone Deacetylase InhibitorsIBA 02/2013 - 01/2005
3	Pharmaceutical PreparationsIBA 01/2012 - 11/2004
3	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2012 - 11/2004
3	Retinoid X Receptors (Retinoid X Receptor)IBA 01/2011 - 10/2005
3	promyelocytic leukemia-retinoic acid receptor alpha fusion oncoproteinIBA 02/2010 - 05/2002
3	Retinoic Acid Receptor alphaIBA 11/2007 - 02/2004
2	Death Domain ReceptorsIBA 01/2017 - 10/2005
2	Transcription Factors (Transcription Factor)IBA 01/2016 - 06/2011
2	Peptides (Polypeptides)IBA 01/2015 - 02/2010
2	AcidsIBA 02/2013 - 01/2010
2	Valproic Acid (Depakote)FDA LinkGeneric 02/2013 - 01/2007
2	4- (2- (5,6,7,8- tetrahydro- 5,5,8,8- tetramethyl- 2- naphthalenyl)- 1- propenyl)benzoic acidIBA 09/2007 - 12/2004
1	Am 580 (Am580)IBA 01/2018
1	Bexarotene (LGD1069)FDA Link 08/2015
1	HeterochromatinIBA 04/2015
1	Biomarkers (Surrogate Marker)IBA 04/2015
1	Sulfides (Thioethers)IBA 01/2015
1	DisulfidesIBA 01/2015
1	Thyroid HormonesIBA 01/2012
1	Triglycerides (Triacylglycerol)IBA 01/2012
1	Anti-Obesity Agents (Antiobesity Drugs)IBA 01/2012
1	CaspasesIBA 01/2012
1	Caspase 3 (Caspase-3)IBA 01/2012
1	Cyclin B1IBA 01/2012
1	PolyphenolsIBA 01/2012
1	UVI5008IBA 12/2011
1	DNA (Deoxyribonucleic Acid)IBA 09/2011
1	TNF-Related Apoptosis-Inducing LigandIBA 09/2011
1	Decitabine FDA Link 09/2011
1	ferroceneIBA 08/2011
1	CateninsIBA 04/2011
1	ResveratrolIBA 02/2010
1	Etoposide (VP 16)FDA LinkGeneric 01/2010
1	NF-kappa B (NF-kB)IBA 01/2010
1	Contraceptive Agents (Contraceptives)IBA 01/2010
1	Abortifacient Agents (Abortifacients)IBA 01/2010
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2009
1	U 0126 (UO 126)IBA 09/2009
1	Biological ProductsIBA 01/2008
1	AntigensIBA 11/2007
1	SiliconIBA 09/2007
1	CarbonIBA 09/2007
1	4- (2- (5,6,7,8- tetrahydro- 3,5,5,8,8- pentamethyl- 2- naphthalenyl)- 1- propenyl)benzoic acidIBA 09/2007
1	Retinoic Acid Receptors (Retinoic Acid Receptor)IBA 01/2007
1	GlucocorticoidsIBA 01/2007
1	Protein Isoforms (Isoforms)IBA 01/2007
1	retinoic acid receptor betaIBA 01/2007
1	Messenger RNA (mRNA)IBA 12/2005
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 10/2005
1	Initiator CaspasesIBA 10/2005
1	Phosphodiesterase InhibitorsIBA 10/2005
1	Interferon Regulatory Factor-1 (Interferon Regulatory Factor 1)IBA 08/2004
1	Histones (Histone)IBA 08/2004
1	InterferonsIBA 08/2004
1	Antineoplastic Agents (Antineoplastics)IBA 08/2004

Therapy/Procedure

18	Therapeutics 01/2022 - 05/2002
2	Chemoprevention 01/2010 - 11/2004
1	Radiotherapy 01/2008
1	Drug Therapy (Chemotherapy) 02/2004